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Oil Adjuvants

We offer large range of ready-to-use adjuvant for animal health. Using emulsion, nano-emulsion or polymer technology, these adjuvants under the brand MONTANIDE are designed to improve vaccine efficiency, safety and stability. These adjuvants ensures stable, efficient vaccine with minimal side effects. Our range of vaccine adjuvants include:

MONTANIDE ISA (Emulsions)

They are used to induce short-term, long-term or both types of protective immune responses to produce various types of emulsions – Water-in-Oil (W/O), Oil-in-Water (O/W), or Water-in-Oil-in-Water (W/O/W).

These powerful, highly refined, and ready-to-emulsify adjuvants are based on non mineral oil, mineral oil or a combination of both, as well as specific surfactant chemistry. The application of the final formulated vaccine determines the type of emulsion, the type of oil as well as the ratio to be used.

Listed below are the types of MONTANIDE ISA.

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MONTANIDE ISA 50 V2

Description
Benefits
Application
Targeted Species
  • Ready-to-use oily vaccine adjuvant for water-in-oil (W/O) emulsion
  • Based on high-grade injectable mineral oil
  • Produces stable vaccine emulsions with low viscosity
  • Easy to inject
  • Induces a strong, long-lasting immune response
  • Recommended for inactivated vaccines and for parenteral administration.
Cattle, Sheep, Goat

MONTANIDE ISA 61 VG

Description
Benefits
Application
Targeted Species
  • Ready-to-use oily vaccine adjuvant for water-in-oil (W/O) emulsion
  • Based on specific enriched light mineral oil and improved surfactant system.
  • Produces stable vaccine emulsions with low viscosity
  • Induces a strong, long-lasting immune response
  • Strong stimulation of cellular immune response
  • Flexible, robust adjuvant recommended for complex antigenic medium that destabilize emulsions.
  • Recommended for inactivated vaccines and for parenteral administration.
  • Designed to increase the Th 1 response compared to traditional oil adjuvants
Cattle, Sheep, Goat, Poultry

MONTANIDE ISA 206 VG

Description
Benefits
Application
Targeted Species
  • Ready-to-use oily vaccine adjuvant for water-in-oil-in-water (W/O/W) emulsion
  • Based on high-grade injectable mineral oil
  • Produces double-emulsion vaccine very fluid and stable
  • Well tolerated
  • W/O/W in one-step manufacturing process
  • Induces short- and long-term immune responses
  • Recommended for inactivated or live vaccines
  • Recommended for parenteral administration
Cattle, Sheep, Goat, Pig

MONTANIDE ISA 201 VG

Description
Benefits
Application
Targeted Species
  • Ready-to-use oily vaccine adjuvant for water-in-oil-in-water (W/O/W) emulsion
  • Based on specific enriched light mineral oil
  • Produces double-emulsion vaccine very fluid and stable
  • Well tolerated
  • W/O/W in one-step manufacturing process
  • Strong stimulation of cellular immune response
  • Induces short- and long-term immune responses
  • Recommended for inactivated or live vaccines
  • Recommended for parenteral administration
Cattle, Sheep, Goat and Pig

MONTANIDE ISA 71 VG

Description
Benefits
Application
Targeted Species
  • Ready-to-use oily vaccine adjuvant for water-in-oil (W/O) emulsion
  • Based on specific enriched light mineral oil
  • Produces stable vaccine emulsions with low viscosity
  • Easy to inject
  • Strong stimulation of cellular immune response
  • Induces a strong, long-lasting immune response
  • Recommended for inactivated vaccines and for parenteral administration.
  • Designed to increase the Th 1 response compared to traditional oil adjuvants
Poultry

MONTANIDE ISA 25 VG

Description
Benefits
Application
Targeted Species
  • Ready-to-use oily vaccine adjuvant for oil-in-water (O/W) emulsion
  • Based on high-grade injectable mineral oil
  • Produces stable vaccine emulsion using simple mixing
  • Very fluid, well-tolerated emulsion
  • Induces a strong short-term immune response
  • Recommended for inactivated or live vaccines
  • Recommended for parenteral administration
Pigs, Ovine

MONTANIDE IMS (Micro-Emulsions)

These are ready-to-dilute adjuvants, especially designed for producing extremely safe veterinary vaccines. These powerful, highly refined and ready-to-disperse adjuvants used to induce rapid immune responses, and are suitable for wide variety of ‘inactivated’ or modified ‘live’ antigens (bacterial, viral, mycoplasma or subunit). They are also suitable for ‘parenteral’ or ‘mucosal’ administration.

These adjuvants are liquid particles available in different sizes from 10 to 500 nm, and distributed over a wide area in an aqueous phase, comprising of an immunostimulating compound. Product contain low amount of oil and are commercially available in preserved (PR) or sterilized (ST) grades. The ratio of use can be adjusted from 15% to 50%, depending on the product selection and the expected safety and efficacy balance.

Listed below are the types of MONTANIDE IMS :

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MONTANIDE IMS 1312 VG

Description
Benefits
Application
Targeted Species
  • Ready-to-dilute aqueous adjuvant containing liquid particles and an immunostimulating compound listed as a GRAS substance (Generally Recognized As Safe).
  • MONTANIDE IMS 1312 VG is commercially available in PReserved grade (PR).
  • Produces a stable, fluid vaccine using simple mixing
  • Good balance between innocuity and efficacy
  • Induces a strong short-term immune response
  • Recommended for mass vaccination immersion
  • Recommended for inactivated or live vaccines
  • Recommended for parenteral or mucosal administration
Fish

MONTANIDE IMS 1313 VG

Description
Benefits
Application
Targeted Species
  • Ready-to-dilute aqueous adjuvant containing liquid particles and an immunestimulating compound listed as a GRAS substance (Generally Recognized As Safe).
  • MONTANIDE IMS 1313 VG is commercially available in PReserved (PR) or STerilized (ST) grades, and can be also formulated as a Neutral reference (N) for use in the presence of phosphate buffer saline (PBS) in antigenic medium.
  • Produces a stable, fluid vaccine using simple mixing
  • Well tolerated, improves the innocuity of the vaccine (can be used with crude antigens or sensitive animals)
  • Induces a strong short-term immune response
  • Recommended for inactivated or live vaccines
  • Recommended for parenteral or mucosal administration
Pigs

MONTANIDE IMS 3012 VG ST

Description
Benefits
Application
Targeted Species
  • Ready-to-dilute aqueous adjuvant containing liquid particles and an immunostimulating compound listed as a GRAS substance (Generally Recognized As Safe).
  • MONTANIDE IMS 3012 VG ST is sterile (terminal sterilization) and contains no oil.
  • Produces a stable, fluid vaccine using simple mixing
  • Well tolerated, improves the innocuity of the vaccine (particularly relevant when dealing with sensitive animals)
  • Induces a strong short-term immune response
  • Recommended for inactivated vaccines.
  • Recommended for parenteral administration
Horse

MONTANIDE GEL (Polymers)

These are highly innovative and ready-to-disperse proprietary polymeric adjuvant that comprises of highly stable polymer (sodium polyacrylate) gel particles widely distributed in water. The depot effect with slow release because of polymer adsorption improves the recruitment of the innate immune system. Thus, these kind of adjuvants enable enhancement of the immune response among animal species, with a ‘safety profile’ identical to aluminium salts.

These adjuvants are particularly suitable for aqueous vaccines (‘live’ or ‘inactivated’) to improve their ability to produce desired results in a safe manner, as well as for ‘mucosal’ or ‘parenteral’ administration.

Listed below are the types of MONTANIDE GEL :

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MONTANIDE GEL 01

Description
Benefits
Application
Targeted Species
  • MONTANIDE GEL is an innovative, ready-to-disperse polymeric adjuvant designed to improve the safety and efficacy of aqueous vaccines.
  • MONTANIDE GEL is commercially available in PReserved (PR) or STerilized (ST) grades.
  • Low usage amount
  • Ready to use and easy to disperse
  • Produces a stable, extremely fluid vaccine by simple mixing
  • Well tolerated, improves the innocuity of the vaccine (can be used with crude antigens and/or sensitive animals)
  • Induces a strong, fast-onset immune response
  • Recommended for inactivated and live vaccines
  • Recommended for parenteral or mucosal administration
Bovine, Ovine, Pig

MONTANIDE PET GEL A

Description
Benefits
Application
Targeted Species
  • MONTANIDE PET GEL A is an innovative, ready-to-disperse polymeric adjuvant designed to improve the safety and efficacy of vaccines for companion animals. It is a sterile adjuvant manufactured in a dedicated pharmaceutical workshop under GMP-like conditions. Equivalent Quality Assurance policy is applied for injectables for both human and pet adjuvants
  • Low usage amount
  • Grade under Quality Assurance supervision, manufactured in a pharmaceutical workshop
  • Produces a stable, extremely fluid vaccine using simple mixing
  • Well tolerated, safety profile similar to aluminium salts
  • Induces a strong, fast-onset immune response
  • Recommended for inactivated or live vaccines
  • Recommended for parenteral or mucosal administration
Dog, Cat, Horse